From Cyclotrons to Cytochromes: Essays in Molecular Biology and Chemistry makes a speciality of the makes use of of the cyclotron and radioactive isotopes in molecular biology and chemistry. The publication contains a tribute to Martin Kamen, who performed an incredible position within the improvement of biochemical sciences within the usa, fairly via his study at the cyclotron. The textual content additionally records study on isotopes performed on the Radiation Laboratory of the collage of California at Berkeley in the course of the Nineteen Thirties, in addition to the function of radioactive carbon in bacterial metabolism and experimental paintings on cytochromes.
This quantity is geared up into six sections encompassing fifty four chapters and starts with an summary of technological know-how and know-how, after which discusses carbon-14 and its half-life. the subsequent chapters talk about the chemistry and constitution of cytochromes; the function of cytochromes and redox platforms in photosynthesis; the organic facets of phosphorylation and oxidation; and protein constitution. The e-book additionally methodically explains the regulatory mechanisms and miscellaneous metabolic strategies comparable to the metabolism of cyclic nucleotides and similar compounds; organic features of lactate dehydrogenase; and nucleotide excision fix of broken DNA. the ultimate bankruptcy discusses the deamidation of asparagine and glutamine facet chains while integrated into polypeptide chains, as regards to the function of cryptic amidase energetic websites in catalyzing the method.
This publication is a necessary source for biochemists and molecular biologists.
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