By M. A. Aon, D. Lloyd, V. Saks (auth.), Miguel A. Aon, Valdur Saks, Uwe Schlattner (eds.)
Systems Biology represents a brand new paradigm aiming at a whole-organism-level figuring out of organic phenomena, emphasizing interconnections and useful interrelationships instead of part components. The learn of community homes, and the way they keep an eye on and control habit from the mobile to organism point, constitutes a primary concentration of platforms Biology. This booklet addresses from a singular point of view a massive unsolved organic challenge: figuring out how a telephone works and what is going flawed in pathology. the duty undertaken by means of the authors is in equivalent components conceptual and methodological, integrative and analytical, experimental and theoretical, qualitative and quantitative, didactic and accomplished. basically, they get to the bottom of the spatio-temporal unfolding of interacting mass-energy and data networks on the mobile and organ degrees, in addition to its modulation via activation or repression by way of signaling networks to supply a definite phenotype or (patho)physiological reaction.
Starting with the ancient roots, in 13 chapters this paintings explores the platforms Biology of signaling networks, mobile constructions and fluxes, organ and microorganism services. In doing so, it establishes the foundation of a twenty first century method of organic complexity.
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